tag:blogger.com,1999:blog-78757891555388523882024-02-07T10:29:02.482-08:00Confessions of a Woman ChemistJanet Jefferyhttp://www.blogger.com/profile/02373291527421734877noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-7875789155538852388.post-19054600280548898132014-10-14T03:52:00.001-07:002014-10-14T03:52:22.539-07:00It is a successive issue<div dir="ltr" style="text-align: left;" trbidi="on">
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It is a successive issue. You are going to begin a test, so you've watched that the gear will be free, you've arranged your examples and now you simply need to weaken from a collective cradle stock. Very regularly there is just a spill left, so you need to make a new load of cradle before you begin, deferring your trial by valuable minutes. Your next stop is the shared concoction stocks, where you discover there is either nothing left or such a silly sum, to the point that it is of no utilization to anybody. This frequently prompts snide mutterings of 'how kind', or something rather more foul. </div>
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I would say, this is particularly basic with combustible solvents. As these need to be kept in an unique vented pantry, there is just a restricted measure of space for the enormous tan flasks they are conveyed in. The way of the containers themselves additionally plans to make everything excessively simple to get got out: you weigh ahead of time that there is a container of dissolvable accessible, see one in the pantry and unwind into the following assignment. Obviously, when you require it, the tan jug has disguised the way that there is just a drop left, never entirely enough for what you have to do. </div>
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So how does a baffled physicist manage this circumstance? There are a few choices: you can go to the on location concoction stores and purchase another one (expecting they are open and have what you require in stock); you can go disagreeing gatherings to check whether you can obtain some; or you can essentially relinquish your half made support or try and do something else. </div>
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Actually for the prestigiously amiable English researcher, over and again purchasing a substitution jug of the same dissolvable – despite the fact that you utilize just a little sum each one time – can test the quietness. You wind up unobtrusively enquiring to discover who else is utilizing it, so you can respectfully propose they quit abandoning it in such a maddeningly futile state. Inexorably, your kindred lab natives will just own up to utilizing a little sum (never an extensive volume, gee golly), and they generally leave bounty in the jug after utilization. </div>
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So where is whatever is left of the dissolvable going? As a researcher, I need to discount untestable theories like 'the arrangement mysteriously vanishes'. I've likewise never seen a partner drinking a mug of cushion (however it has struck me that they may), so either that isn't the clarification or they're exceptionally unpretentious about it. The responses to these inquiries might never found, yet every time it happens you set out to check all the more completely before each one arranged trial. Until whenever, obviously.</div>
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Janet Jefferyhttp://www.blogger.com/profile/02373291527421734877noreply@blogger.com0tag:blogger.com,1999:blog-7875789155538852388.post-62751889465928287482013-03-05T02:59:00.002-08:002013-03-05T02:59:40.498-08:00Jennifer A. Doudna<div dir="ltr" style="text-align: left;" trbidi="on">
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<span style="font-size: 13.0pt; line-height: 115%;">Jennifer A. Doudna Ph.D. is a Professor of Chemistry and of
Molecular and Cell Biology at the University of California, Berkeley. She has
been an investigator with the Howard Hughes Medical Institute since 1997. She
earned her B.A. in Chemistry from Pomona College and her Ph.D. in Biochemistry
from Harvard University on ribozymes under the mentorship of Jack W. Szostak.
She did her postdoctoral work with Thomas Cech at the University of Colorado,
Boulder.</span></div>
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<span style="font-size: 13.0pt; line-height: 115%;">While in the Szostak lab, she reengineered the self-splicing
Group I catalytic intron into a true catalytic ribozyme that would copy RNA
templates. Recognizing the limitations of not being able see the molecular
mechanisms of the ribozymes. She started work to crystallize and solve the
three-dimensional structure of the Tetrahymena Group I ribozyme in 1991 in the
Cech Lab and continued while she started her professorship at Yale University
in 1994. </span></div>
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<span style="font-size: 13.0pt; line-height: 115%;">While the group was able to grow high-quality crystals, they
struggled with the phase problem due to unspecific binding of the metal ions.
One of her early graduate students and later her husband, Jamie Cate decided to
soak the crystals in osmium hexamine to imitate magnesium. Using this strategy,
they were able to solve the structure, the second solved folded RNA structure
since tRNA. The magnesium ions would cluster at the center of the ribozyme and
would serve as a core for RNA folding similar to that of a hydrophobic core of
a protein.</span></div>
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<span style="font-size: 13.0pt; line-height: 115%;">Jennifer was promoted to be the Henry Ford II Professor of
Molecular Biophysics and Biochemistry at Yale in 2000. In 2002, she accepted a
faculty position at University of California, Berkeley as a Professor of
Biochemistry and Molecular Biology so that she would be closer to family and
the synchrotron at Lawrence Berkeley National Laboratory. This initial work to
solve large RNA structures lead to further structural studies on the HDV
ribozyme, the IRES, and protein-RNA complexes like the Signal recognition
particle. Her lab now focuses on obtaining a mechanistic understanding of
biological processes involving RNA.</span></div>
<div class="MsoNormal" style="text-align: justify;">
<br /></div>
<div class="MsoNormal" style="text-align: justify;">
<span style="font-size: 13.0pt; line-height: 115%;">This work is divided
over three major areas, the CRISPR system, RNA interference, and translational
control via MicroRNAs. She was a Searle Scholar and received the 1999 NAS Award
for Initiatives in Research and the 2000 Alan T. Waterman Award. She has
received several awards and has been elected to the National Academy of
Sciences in 2002 and the Institute of Medicine in 2010.</span></div>
</div>
Janet Jefferyhttp://www.blogger.com/profile/02373291527421734877noreply@blogger.com0tag:blogger.com,1999:blog-7875789155538852388.post-25184764876619215862012-07-13T02:28:00.002-07:002012-07-13T02:28:34.385-07:00Louise Hammarström<div dir="ltr" style="text-align: left;" trbidi="on">Louise (Lovisa) Katarina Hammarström (born 25 May 1849 - 5 November 1917), was a Swedish chemist. She was the first formally trained and educated Swedish chemist of her gender.<br />
<br />
Louise Hammarström was the daughter of a vicar. Orphaned at an early age, she grew up at an Ironworks in Dalarna, in central Sweden, where she became interested in chemical substances. She studied chemistry by private lessons, and was in 1875 employed at the laboratory of engineer Werner Cronquist in Stockholm, were she was active as an assistant in 1876-1881. She was then active as mineral chemist at the Ironworks of Bångbro (1881–87), Fagersta (1887–91) and Schisshyttan (1891–93). In 1893, she opened her own laboratory, in which she was primarily focused on minerals and geological studies.</div>Janet Jefferyhttp://www.blogger.com/profile/02373291527421734877noreply@blogger.com0tag:blogger.com,1999:blog-7875789155538852388.post-4913062864779496222011-11-02T02:27:00.001-07:002011-11-02T02:27:28.235-07:00Women in Chemistry: Progress Made, but Obstacles Remain<div dir="ltr" style="text-align: left;" trbidi="on"><br />
The world is in the midst of the International Year of Chemistry 2011 (IYC 2011), a global “celebration of the achievements of chemistry and its contributions to the well-being of humankind.” An initiative of the International Union of Pure and Applied Chemistry (IUPAC) and of the United Nations Educational, Scientific, and Cultural Organization (UNESCO), the year-long celebration involves chemical societies, academies and institutions worldwide and is aimed at promoting international scientific collaboration. In support of IYC 2011, close to 100 countries registered more than 600 events and 1,200 activities.<br />
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The year also is focusing on the contributions of women to chemistry as it coincides with the 100th anniversary of the Nobel Prize awarded to Madame Marie Curie, the first woman to win a Nobel Prize in Chemistry. Curie also shared a Nobel Prize in Physics with her husband Pierre Curie and scientist Henri Becquerel.<br />
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Gains and challenges experienced by several SLAS members and their colleagues are representative of how women have moved up the career ladder in chemistry over the years. “In pursuit of female chemists,” a commentary published in the August 18 issue of the journal Nature—as well as feedback from SLAS members—suggests that while some progress has been made, there is still much work to be done.<br />
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In the Nature commentary, Carol Robinson of the University of Oxford, U.K., notes, “The decline from chemistry Ph.D.s (46% women) to professorships (just 6%) is steeper than in other disciplines, including physics and engineering.” Equally disappointing, a recent survey concluded that “one-quarter of all 14-years-olds in the United Kingdom confuse Marie Curie with pop singer Mariah Carey.” Robinson suggests a need for new role models for today’s women, noting that “chemistry… has a macho culture in which getting to the finish line first is more important than how you get there.” In addition, she states, “Too often, female scientists shy away from responsible roles or don’t have sufficient confidence or aspirations.”<br />
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Some of the same themes—pressure on women to excel, different leadership styles and the need to bring more women into the discipline—were also cited by SLAS members before the Nature commentary’s publication. These members had much to say about some of the key issues facing women in chemistry today. They also suggested solutions.</div>Janet Jefferyhttp://www.blogger.com/profile/02373291527421734877noreply@blogger.com0tag:blogger.com,1999:blog-7875789155538852388.post-44528888036888214392011-09-20T00:51:00.001-07:002011-09-20T00:51:51.794-07:00Women chemists<div dir="ltr" style="text-align: left;" trbidi="on"><br />
B<br />
Leslie Barnett<br />
Irina Beletskaya<br />
Ruth R. Benerito<br />
Helen M. Berman<br />
Carolyn R. Bertozzi<br />
Hazel Bishop<br />
Rachel Fuller Brown<br />
<br />
C<br />
Emma P. Carr<br />
Mildred Cohn<br />
Marie Curie<br />
<br />
F<br />
Mary Peters Fieser<br />
Rosalind Franklin<br />
Helen Murray Free<br />
Elizabeth Fulhame<br />
<br />
G<br />
Louise Giblin<br />
Mary L. Good<br />
<br />
H<br />
Anna J. Harrison<br />
Dorothy Hodgkin<br />
<br />
I<br />
Clara Immerwahr<br />
<br />
J<br />
Allene Jeanes<br />
Irène Joliot-Curie<br />
Joyce Jacobson Kaufman<br />
<br />
K<br />
Ann Kiessling<br />
Stephanie Kwolek<br />
<br />
L<br />
Jeehiun Lee<br />
Jing Li<br />
Kathleen Lonsdale<br />
Louise Hammarström<br />
<br />
M<br />
Maud Menten<br />
Angela Merkel<br />
N<br />
Elizabeth Ann Nalley<br />
Dorothy M. Needham<br />
Pauline Newman<br />
O<br />
Wilma Olson<br />
P<br />
Marie-Anne Pierrette Paulze<br />
Lucy Weston Pickett<br />
Agnes Pockels<br />
R<br />
Hazel Alden Reason<br />
Ellen Swallow Richards<br />
S<br />
Katsuko Saruhashi<br />
Patsy O'Connell Sherman<br />
Maxine Singer<br />
Hertha Sponer<br />
Anna Sundström<br />
T<br />
Mária Telkes<br />
Margaret Thatcher<br />
Alice Y. Ting<br />
U<br />
Kathryn Uhrich<br />
W<br />
Karen Wetterhahn<br />
Elsie Widdowson<br />
</div>Janet Jefferyhttp://www.blogger.com/profile/02373291527421734877noreply@blogger.com0